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位置: 首页 > 抗体 > Recombinant Tau(Phospho-Thr181) Rabbit mAb(G69)

Recombinant Tau(Phospho-Thr181) Rabbit mAb(G69) #58002

Recombinant Tau(Phospho-Thr181) Rabbit mAb(G69)
是否有货: yes
产品总价:
产品详情

产品名称Recombinant Tau(Phospho-Thr181) Rabbit mAb(G69)

来源种属Rabbit

克隆性Monoclonal

克隆性G69

纯化Affinity purification

应用WB,ELISA

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of Tau only when phosphorylated at threonine 181.

免疫原类型Peptide

免疫原描述Peptide sequence around phosphorylation site of threonine 181 derived from Human Tau.

基因/蛋白名称Tau

修饰Phospho

别名MAPT; MTAPT; MTBT1; Neurofibrillary tangle protein; PHF-tau

数据库入口号Swiss-Prot: P10636
NCBI Protein: NP _001116538.1

浓度0.8 mg/ml

配方PBS with 0.02% sodium azide,pH7.3.

保存Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.

应用详情

 Predicted MW: 48 62 78 kd
Western blotting: 1:500~1:1000

Western blot analysis of extracts from 293 cells, transfected with Tau and treated with calf intestinal phosphatase (CIP) using Tau(Phospho-Thr181) Rabbit mAb.
背景

  Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 

Puig B, et al.(2005) Acta Neuropathol (Berl). 110(3):261-268. 
 

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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